Cell-Surface Bound Nonreceptors and Signaling Morphogen Gradients
نویسندگان
چکیده
منابع مشابه
Cell-Surface Bound Nonreceptors and Signaling Morphogen Gradients.
The patterning of many developing tissues is orchestrated by gradients of signaling morphogens. Included among the molecular events that drive the formation of morphogen gradients are a variety of elaborate regulatory interactions. Such interactions are thought to make gradients robust, i.e. insensitive to change in the face of genetic or environmental perturbations. But just how this is accomp...
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Individuals of the same or closely related species can vary substantially in size. Still, the proportions within and between tissues are precisely kept. This adaptation of pattern with size termed scaling, is receiving a growing attention. We review experimental evidence for scaling, and describe theoretical models for mechanisms that scale morphogen gradients. We particularly note the Expansio...
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Shh activity and at different distances from the source. The proper functioning of tissues and organs requires These observations provide unequivocal evidence that that each cell differentiate appropriately for its position. Shh acts directly on distant cells and therefore that Shh In many cases, the positional information that instructs forms a morphogen gradient in the developing neural cells...
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ژورنال
عنوان ژورنال: Studies in Applied Mathematics
سال: 2014
ISSN: 0022-2526
DOI: 10.1111/sapm.12030